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Sqrutiny sketcher
The question of orthogonality is inherent to the endeavor of creating standards in Synthetic Biology, although few systematic approaches have been proposed yet. In a

What is a chassis in Synthetic Biology?
A chassis is defined as the load-bearing framework of an object. In other words, the chassis supports the weight and the structure of the object

Engineered bacteria as an early-stage drug discovery platform against diseases caused by protein misfolding and aggregation
Protein misfolding and aggregation are common pathological features for many human diseases, such as Alzheimer’s disease, type 2 diabetes, amyotrophic lateral sclerosis and cancer. Aiming

Engineering a Thermophilic Microbial Chassis for Synthetic Biology Applications
The OMIC-Engine Athens Hub is working on incorporating the advantages of high-temperature biocatalysis into Synthetic Biology (SB) applications. Led by the Enzyme and Microbial Biotechnology

Refactoring the Conjugation Machinery of Promiscuous Plasmid RP4
Chromosomal exchange and subsequent recombination of the cognate DNA between bacteria was one of the most useful genetic tools (e.g., Hfr strains) for genetic analyses

The long and winding road: accidents and tinkering in software standardization
Software is based on universal principles but not its development. Relating software to hardware is never automatic or easy. Attempts to optimize software production and