Standardsinsybio

For the sake of the Bioeconomy: define what a Synthetic Biology Chassis is!

The role of synthetic biology as a fuel for the bioeconomy requires clarification of the terms typically adopted by this growing scientific-technical field. In particular, the concept of ‘chassis’ as a defined, reusable biological frame where non-native components can be plugged in and out to create new functionalities lies at the boundary between frontline bioengineering and more traditional recombinant DNA technology.

This work reviews the state of the ongoing discussion on what is a chassis, with a special focus on a non-equivocal nomenclature for the jargon used and a number of objective criteria recommended for distinguishing synthetic biology agents from traditional GMOs.

Check out the full Open Access article available online here.

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