How to quantify a genetic firewall? A polarity‐based metric for genetic code engineering

Genetic code engineering aims to produce organisms that translate genetic information in a different way from that prescribed by the standard genetic code, which can eventually lead to organisms that operate under different genetic codes. And, if two organisms operate under different genetic codes, how likely is it that they can still correctly interpret each … Leer más

Concomitant prediction of environmental fate and toxicity of chemical compounds

The environmental fate of many functional molecules that are produced on a large scale as precursors or as additives to specialty goods (plastics, fibers, construction materials, etc.) is generally unknown. Assessing their environmental fate is crucial when making decisions on the manufacturing, handling, usage, and release of these substances, as is the evaluation of their … Leer más

Initiating the interface between science, industry and risk assessment authorities: notes from the BioRoboost workshop

The need to be able to perform reliable risk assessments in synthetic biology research and for its applications has been identified as a key obstacle to assuring safety of products and mitigating any risks of synthesized microbes in the case of escape for laboratories. Without these assurances widespread use and acceptance of the products of synthetic biology … Leer más

Towards enhanced biosafety and risk assessment standards in synthetic biology, a workshop in Heidelberg (Germany)

As part of Work Package 6 of BioRoboost, a workshop to look at technical and policy gaps in the use of and need for standards to improve risk assessment and enhance biosafety in synthetic biology was held 7-9 October 2019 in Heidelberg, Germany. This workshop, “Towards enhanced biosafety and risk assessment standards in synthetic biology”, was … Leer más